Estrigenix Therapeutics, Inc. presents at 2nd ACE Drug Discovery Summit 2024 in London

MILWAUKEE (March 21, 2024) – Estrigenix Therapeutics, Inc., a Wisconsin-based, privately held pharmaceutical company leading the way in estrogen biology, is proud to have been a presenter at the ACE Drug Discovery Summit 2024 in London.

William Donaldson, Ph.D., chief executive officer (CEO) of Estrigenix presented an abstract entitled, “Discovery of Selective Estrogen Receptor Beta Agonists as Therapeutics for Hot Flashes and Memory Dysfunction.” The presentation highlighted original Estrigenix research on potentially safe alternatives to traditional estrogen therapy (ET).

“The dramatic decline in the production of estrogen during menopause can result in hot flashes, sleep disruption, memory dysfunction, anxiety, and depression in many women,” explained Donaldson. “While traditional ET addresses these symptoms, ET has associated risks for breast cancer and blood clots leading to stroke. For this reason, many OB/GYNs will not prescribe ET for the 13 percent of menopausal women with a history of breast or uterine cancer or stroke.”

Additionally, some women, who are not in these high-risk categories, avoid taking estrogen due to the perceived health risks. Traditional HT is a double-edged sword due to the presence of two estrogen receptors, ER alpha and ER beta. ER beta is known to control vasomotor symptoms while ER alpha is associated with the proliferation of 80 percent of breast cancer cell lines. Thus, highly selective ER beta agonists have the potential to be a safe alternative to traditional HRT.

The ACE Drug Discovery Summit provides a platform for scientists, researchers and decision makers from all over the world to debate on the latest scientific advances, trends, current challenges and futuristic advancements in Drug Discovery. The two day conference is designed to maximize collaborations and innovation with pharma and technology presentations, interactive sessions by professionals from industry and academia.

To learn more about Estrigenix and how this new therapy is helping women improve their quality of life, visit estrigenix.com.

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About Estrigenix Therapeutics, Inc.

Estrigenix Therapeutics, Inc. is a Wisconsin-based, privately held pharmaceutical company leading the way in research and progress in estrogen biology. There is a known correlation between the severity of a woman’s hot flashes and her increased risk of developing dementia later in life. Estrigenix was formed in 2018 to develop and commercialize first-in-class therapeutics to treat and prevent hot flashes and dementia in post-menopausal women with fewer side effects than current hormone replacement therapy.

For more information and to learn how Estrigenix is pioneering the way in dementia prevention for post-menopausal women, visit estrigenix.com.

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Estrigenix Therapeutics is a registered trademark of Estrigenix Therapeutics, Inc.