Estrigenix Therapeutics, Inc. honored to have presented at Women’s Healthy Aging Innovation Summit 2022 in San Diego

MILWAUKEE (November 16, 2022) – Estrigenix Therapeutics, Inc., a Wisconsin-based, privately held pharmaceutical company leading the way in estrogen biology, was selected as the winner for the ‘Alzheimer’s & Brain Health’ Category among all presenting companies, for demonstrating the most innovative work in the Alzheimer’s, dementia, and brain health sector.

Karyn Frick, Ph.D., chief science officer (CSO) of Estrigenix, presented at the Women’s Healthy Aging Innovation Summit 2022 in San Diego on November 9, 2022. Her presentation, entitled, “Discovery of Selective ER Beta Agonists as Potential Therapeutics to Treat Hot Flashes and Memory Dysfunction in Menopausal Women” highlighted original Estrigenix research on potentially safe alternatives to traditional hormone therapy (HT).

“In the US alone, there are over sixty million menopausal women, and 80 percent experience symptoms including hot flashes and memory dysfunction. The severity and frequency of hot flashes are correlated with an increased risk for Alzheimer’s disease, which may help to explain why 2/3 of Alzheimer’s patients are women,” explained Frick. “Having a treatment that address hot flashes and memory  dysfunction, but avoids the potential risks associated with traditional hormone therapy, such as cancer and stroke, would provide significant benefits for women.”

The dramatic decline in the production of estrogen during menopause can result in hot flashes, sleep disruption, memory dysfunction, anxiety, and depression in many women. Although traditional HT addresses these symptoms, HT has associated risks for breast cancer and blood clots leading to stroke. For this reason, many OB/GYNs will not prescribe HT for the 19 percent of menopausal women with a history of breast or uterine cancer or stroke.

Additionally, some women who are not in these high-risk categories avoid taking estrogen due to the perceived health risks.

The Women’s Healthy Aging Innovation Summit focused on addressing and bringing awareness to challenges and unmet needs for menopausal women and their health. Bringing together industry leaders, including those in finance and research, the meeting dedicated time to accelerating innovation, investment, research and partnerships to improve access to quality of care for menopausal women worldwide.

To learn more about Estrigenix and how its technology may help improve women’s quality of life, visit


About Estrigenix Therapeutics, Inc.

Estrigenix Therapeutics, Inc. is a Wisconsin-based, privately held pharmaceutical company leading the way in research and progress in estrogen biology. Estrigenix was formed in 2018 to develop and commercialize first-in-class therapeutics to treat and prevent symptoms of menopause, including hot flashes and dementia, with fewer side effects than current hormone therapies.

For more information and to learn how Estrigenix is pioneering the way in symptom prevention for menopausal women, visit

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