Estrigenix Therapeutics, Inc. presents new hormone replacement therapy research at the 10th Drug Discovery Strategic Summit

MILWAUKEE (Oct. 25, 2022) – Estrigenix Therapeutics, Inc., a Wisconsin-based, privately held pharmaceutical company leading the way in estrogen biology, is presenting at the 10th Drug Discovery Strategic Summit on Thursday, October 27, and Friday, October 28 at the Grand Hyatt at San Francisco airport, located at 55 South McDonnell Road in San Francisco. 

Estrigenix’s chief executive officer (CEO), William Donaldson, Ph.D. is presenting an abstract called, “Discovery of Selective Estrogen Receptor Beta Agonists as Therapeutics for Hot Flashes and Memory Dysfunction.” The presentation focuses on original Estrigenix research on potentially safer alternatives to traditional hormone replacement therapy (HRT).

Many women experience a dramatic decline in the production of estrogen during menopause which can result in hot flashes, sleep disruption, memory dysfunction, anxiety, and depression. Traditional HRT addresses these symptoms, but it has been linked to an increased risk of breast cancer and blood clots leading to stroke.

“Original HRT, while it addresses the symptoms of menopause is known to cause other health problems due to the presence of two estrogen receptors, ER alpha, and ER beta. ER beta is known to control vasomotor symptoms while ER alpha is associated with the proliferation of 80 percent of breast cancer cell lines,” explained Donaldson. “By developing highly selective ER beta agonists we have the potential to create a safe alternative to traditional HRT that will treat the profound side effects associated with estrogen decline while not increasing a woman’s risk of cancer or stroke.”

The 10th Drug Discovery Strategic Summit is organized by Agile Falcon Strategic Group, which focuses on connecting the life science industry. 

To learn more about Estrigenix and how this new therapy is helping women improve their quality of life, visit


About Estrigenix Therapeutics, Inc.

Estrigenix Therapeutics, Inc. is a Wisconsin-based, privately held pharmaceutical company leading the way in research and progress in estrogen biology. There is a known correlation between the severity of a woman’s hot flashes and her increased risk of developing dementia later in life. Estrigenix was formed in 2018 to develop and commercialize first-in-class therapeutics to treat and prevent hot flashes and dementia in post-menopausal women with fewer side effects than current hormone replacement therapy. 

For more information and to learn how Estrigenix is pioneering the way in dementia prevention for post-menopausal women, visit

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